Guanabenz acetate ( Wy8678 acetate )

Catalog No. M13664 CAS No. 23256-50-0

An α2 adrenergic receptor that is used as an antihypertensive drug.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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500MG	38	In Stock
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Biological Information

Product Name

Guanabenz acetate
Note

Research use only, not for human use.
Brief Description

An α2 adrenergic receptor that is used as an antihypertensive drug.
Description

An α2 adrenergic receptor that is used as an antihypertensive drug; has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex; also has antiparasitic activity against replicative stages of Toxoplasma.Hypertension Approved
Synonyms

Wy8678 acetate
Pathway

Angiogenesis
Target

Adrenergic Receptor
Recptor

α2A-adrenergic receptor; α2B-adrenergic receptor; α2C-adrenergic receptor
Research Area

Cardiovascular Disease
Indication

Hypertension

Chemical Information

CAS Number

23256-50-0
Formula Weight

291.13
Molecular Formula

C10H12Cl2N4O2
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 51 mg/ml
SMILES

NC(N/N=C/C1=C(Cl)C=CC=C1Cl)=N.CC(O)=O
Chemical Name

Hydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-, acetate (1:1)

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42.
2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109.
3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.

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