Guanabenz acetate

CAS No. 23256-50-0

Guanabenz acetate( Wy8678 acetate )

Catalog No. M13664 CAS No. 23256-50-0

An α2 adrenergic receptor that is used as an antihypertensive drug.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 38 In Stock
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Biological Information

  • Product Name
    Guanabenz acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    An α2 adrenergic receptor that is used as an antihypertensive drug.
  • Description
    An α2 adrenergic receptor that is used as an antihypertensive drug; has been proposed to exert protective effects against misfolding by interfering with eIF2α-P dephosphorylation through selective disruption of a PP1-PPP1R15A holophosphatase complex; also has antiparasitic activity against replicative stages of Toxoplasma.Hypertension Approved(In Vitro):Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
  • In Vitro
    Guanabenz is an alpha agonist of the alpha-2 type that is used as an antihypertensive drug. It is used to treat high blood pressure (hypertension).
  • In Vivo
    ——
  • Synonyms
    Wy8678 acetate
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    α2A-adrenergic receptor| α2B-adrenergic receptor| α2C-adrenergic receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Hypertension

Chemical Information

  • CAS Number
    23256-50-0
  • Formula Weight
    291.1339
  • Molecular Formula
    C10H12Cl2N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 51 mg/ml
  • SMILES
    NC(N/N=C/C1=C(Cl)C=CC=C1Cl)=N.CC(O)=O
  • Chemical Name
    Hydrazinecarboximidamide, 2-[(2,6-dichlorophenyl)methylene]-, acetate (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Das I, et al. Science. 2015 Apr 10;348(6231):239-42. 2. Crespillo-Casado A, et al. Elife. 2017 Apr 27;6. pii: e26109. 3. Benmerzouga I, et al. Antimicrob Agents Chemother. 2015 Nov;59(11):6939-45.
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